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Polymer Mechanics Laboratory

Research > MEMS

MEMS technique for characterizing magnetic susceptibility

The effects of magnetic forces are determined by the magnetic susceptibility and mass of a particle. If different subcellular components react to the magnetic field in differing ways due to different magnetic susceptibilities, potentially detrimental internal cell stresses could occur. We have been developing a method to measure these values for subcellular organelles; using a magnetophoresis approach in conjunction with a charged-coupled device (CCD) to track tagged particles in a flow cell. The sensitivity and accuracy of this technique is still being evaluated to ensure measurements can be obtained within the expected range for subcellular organelles. If the individual susceptibilities for the different types of subcellular organelles are identified, it could be possible to target and elicit a specific cellular response as magnetic therapy.

Fig. 1: Subcellular organelles refers to organelles contained within a cell