University of Minnesota
University of Minnesota: Department of Mechanical Engineering

Bioheat and Mass Transfer Laboratory

The bioheat and mass transfer laboratory (BHMT) at the University of Minnesota is dedicated to the study of thermophysical and biological changes within biomaterials after thermal manipulations (esp.. heating or cooling). This work is broadly in the scientific fields of thermal biology including cryobiology (low temperature biology) and hyperthermic biology, with particular focus in the following application areas: (1) Nanomedicine, (2) Thermal Therapies, (3) Cryo and Biopreservation and (4) Thermal/Mechanical Properties.

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The latest area of emphasis in the BHMT lab focuses on the use of iron oxide and gold nanoparticles to enhance thermal therapies. For example, iron oxide can be used for detection and heating of cancer. In addition, gold nanoparticles can be used to deliver drugs or neo-adjuvants and to heat cancer locally by their excitation due to electro-magnetic and optical sources.

Basic investigations of nanoparticle biodistribution and heating at the cellular and tissue level based on nanoparticle type, coating, size, and charge are currently underway. In brief the lab focuses on basic aspects of thermal injury and applied work in the characterization and development of devices for preservation and destruction of cells and tissue using heat or cold.

Participating Faculty: John C. Bischof
Mechanical Engineering 201 and Diehl G-144 (612-625-5513 and 626 4534)

ASME 2014 3rd Global Congress on NanoEngineering for Medicine and Biology
Feb 2-5, 2014 in San Francisco, CA

IEM Cancer Animal Core Laboratory