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Research in this lab includes experimental
and theoretical modeling of high and low temperature heat and
mass transfer in biological systems, with particular emphasis
on phase change phenomena. Current projects include experiments
with quantitative biological microscopy techniques to dynamically,
as well as, statistically observe single cells at supra and subphysiological
temperatures. Experiments on whole tissues are also underway to
investigate the mechanisms of ice formation and damage during
freezing of an organ. Theoretical modeling based on experimental
data for the prediction of supraphysiological thermal injury is
an area of ongoing interest. Predictive models for freezing in
single cells and whole tissues are also being developed. There
are several areas of application of this research in the biomedical
community. In high temperature bioheat and mass transfer, further
understanding and prediction of thermal injury allows for the
possible manipulation and treatment of burned cells and tissues.
Furthermore, the low temperature research allows contribution
to improved cryosurgical and cryopreservation protocols to either
selectively destroy or preserve cells and tissues through freezing.
Participating Faculty: John
C. Bischof
Mechanical Engineering 201 and Diehl G-144 (612-625-5513 and 626
4534) |