University of Minnesota
University of Minnesota: Department of Mechanical Engineering
http://www.me.umn.edu/

 

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Example Imaging and Assessment Protocols (w/collaborators)

Assessment

Method

Outcome

DSFC

 

 

Imaging

Bright field

Inflammation: WBC Rolling

Imaging

Infra-red

Surface temperature change

Imaging

Fluorescence

Perfusion Defect

Histology

Immunohistochemistry

Inflammation: NF-kB, VCAM, CD31

Therapy

Thermal, chemical, electrical and mechanical

Histology and Perfusion Defect


 

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Hindlimb

 

 

Imaging

Photoacoustic lifetime

Tissue oxygenation

Imaging

Infra-red

Surface temperature

Imaging

Contrast enhanced
ultrasound

Blood Flow Index (Vascularity)

Imaging

Dual mode ultrasound array

Treatment and imaging

Imaging

SWIFT MRI

IONP Nanoparticle Biodistribution

Imaging

Contrast Enhanced MR

Vascular Permeability and Flow Change

Mass Spec

Atomic Emission
Spectroscopy

Nanoparticle biodistribution

Perfusion

Microbead assay

Vascular blood pool in organ/tumorover time

Histology

Immunohistochemistry

Inflammation: NF-kB, VCAM, CD31

Therapy

Tumor Growth Delay

Treatment outcome metric